So there could be a button in the setting Macro that switches a function to another function as long as you hold that button down
So just for an example you Hold Q down and that makes switches the left joystick(movement) with the right joystick (movement) until you let go of Q
So for a game like Apex legends when you go to loot a dead body you would hold down Q and you can select loot with the mouse instead of WASD, but as soon as you let go of Q it goes back to wasd for movement and mouse for look movement.
So if you think about its just a profile put instead of on the F1-8 keys its on a bound key and only activates when you hold it down.